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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dff741e498a30e66bffd9bc9b58bcb91616be20b797f8c2414f8545fddbdf150' 
  AND token = 'sFBaCGUb+Y+0hcDgMfa4hRyyouVeDFFYcrdIsirqhhI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}