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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f10d66233b49d424686541a958d656e67892c4706b1f8a4ad5015d50ed89b18c' 
  AND token = 'e3X5KTH04VxFJdg5LiPSKO3BLwjCdps8ev6Q2qVg6q4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}