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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '83603377c5c494935f3d5735b3f14d56c77489fed0fc06874736ffd0e7bca412' 
  AND token = 'jjvb/H6nrdrS+3cDXrpBCFlV9qAH4LfNURq9Zm0N94M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}