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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6944de86482b4f358fc7af438a7982c2f52731860c4f84eae6bdcfe209eaf659' 
  AND token = 'GQ0fPnFte8QyhpoU+W/JW+WiuQmtaeupdZA3sNg4Xio=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00225

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}