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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5867d0e31a080a93877ff5d6b92c6c1e0b11b7ac8348a14dcdc102bf3bf4d738' 
  AND token = 'B/RvP49/A7Yr7fSPn23ZAcmqdnUSRDEgrY0DdEQE4m0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}