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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '749e386183120a859ce7615ba47e221d9cc16feb110771286d598b91df5cced3' 
  AND token = 'QzSW3nYE44Ckg1Pc2caFl0vZSjcSNvcrnAT3Rc06BVU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}