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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afb54d422aa915b920c3042ef4ff25adef6764b84b35f198ab000ba1313a25b3' 
  AND token = 'TPZ+L2Hb7BatJwn7AK+zlfo28W2rehe9xj+PMb8PlnA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}