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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '793d4a9c54b3d95a12de47bbfaa59dab587a4b4342f8f65ef8205dd7be393a49' 
  AND token = 'W6TxSwkCjfWuN4LQDakAuLC1XmCVvd056hy1dn9bJxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}