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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a8046a3e692e3c29e0c4948678ab90a1c37a7940d4e5e3cb655602446d00fc8' 
  AND token = 'MjPWOobUyoHXDV9fpP3vXpu39/R7MTdUes1XVampfU8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}