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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '111eea1d4c919580e05e8535fb5ab0aa30ab39137ca7a6f525f0e81b6fc2be5f' 
  AND token = 'k0NHFWkbkeSL5BRIoniTiM5Mvu3QMXO26zgJ6vNfLpg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}