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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15e8d14d83fa3fd674c10bcfb73d027308f74231ca6ad41c565f9ff1a3766408' 
  AND token = 'tbZUFsbhx5IrCr5dC7m+THchDo/wQwV7V/vomRSC0Oo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}