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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57b431bd1b438877efe555d01e5c039cc7ae70c5e48389a78869e5e46fb6f111' 
  AND token = 'knVTS+ZdNagHgz+URB5RzwpA61JLRNHOYzBHcj5Hh3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}