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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22c64dc65397d7ee8af82cb6f7a3bea428ed5faa23e3272fd05095bf60a758de' 
  AND token = '/OcLhKwTd2MLj+EW8yF55OVn4IJMy+OB6iE8j9x7Tog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}