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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6390c39f3bdcfc3d232a2c5491faa5d6b4ef4b16f882300f29c72783f8cf3d59' 
  AND token = 'kgmGSKxX+hCIbaRGHcDHeRIB2F3zZPrV7f7zbNE2xb8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}