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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c308357f8cb113e1d1298b212c779ec7157efa6fd74b45e8ecf5457d01910cf' 
  AND token = 'KOCYSSx02rmaI24o6qGvzsA+M36PuFX8a0iBYkLBXPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}