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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50e8acecc7e5193c2785fb3894316d131ae61fc5d6358f3b00790e196a2737c0' 
  AND token = '1li+zszub+DtLsrrr5gnQ1LCpMD/QX9Eo8nW8JSB1Qw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}