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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33c0f69289f8f1f4e5e54bdb2712de1287573a63e7e82bbb2a15067e1a79c073' 
  AND token = 'wTcE853UJW0rRxldUwx3drwNxzyhoMX9i3Pl7gSxl6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}