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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '843d79c10c18e75b6a1689d400c2a24156e2e1b24abfae6d78333656c829a555' 
  AND token = '+F4TKPJzrcYb9n7x4kDs4zfq3GMBubTn26PYbGenD7E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}