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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6b56e0a4f536aad95cdf1eb5d49109c4a1a1106477045b98b52a9cd1b08b8d6' 
  AND token = 'EXqfwTzDWT0dvSw47VNSMyCWsvHuYq3O3VC03Bn7amM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}