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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '826647d889894e0d30401d8f3b8214a20442ce58edb5a484afaf4410f6be304a' 
  AND token = 'nN3+RUu3LGFlY3X8xkXy3oGt8QjuAY/CDHMhnAfx4YY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}