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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d80b824eedd7bc4cf51d715ea864b5b653551477ce7f564b1eb1dc67384986f' 
  AND token = 'rvFhSPR3WbxVybK66KZV0hPTAhTvu/CdExhGuNpsvp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}