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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf07f05c21fb3de0f1a7e2b7417b1104d07dd49e69d4b980ea458e84b02fda01' 
  AND token = '+myloTDcvfC3Gi/IxNDyNfEwnebxaT3GTUbba6BOTs4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}