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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac69b222e077040fb1887ec2c9de1fc6be383fc838e9c69b7f6bba61aba008d5' 
  AND token = '3svK+OfeOGB1dw9fDYmUFUrolGD2qPLcciy9VNoL8uM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}