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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59c751a0ecb10aea9c3b3addbc4d48d60d974a90d71e59ffa3998a0d6154c08e' 
  AND token = 'dMDek2dAEahxSlhEaMAYyS6OPBsQK8ZGM7U7nOfaj/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}