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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8c2e5ccf7da8debec666845d67d7770154c5f01504f469a284f5df54a14d8b4' 
  AND token = 'dIgUs2hYN3+Fh/yOO8rK8nYFPxtTgC2GMIXAjTXyEAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}