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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f5cbf27b1df2f3da44596e92f55f1160019f9e84dbd760de48d27c41ebcf642' 
  AND token = 'nsGqZO+2wzk/xfBqtaNSFbsJSxLIIN1Hgyi9Lk4oNJA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00094

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}