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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de162e1d23d039097681035604b081379cd3f29d006f6d552f747e996a536f90' 
  AND token = '76lPOKlcuXcsQ6pTfk5ZuzRSp8g4/H7CY7cGypUcCyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}