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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74504597682daa6808a0209b20e164167cac25ddf1cfd0db6d97924a9d8346e9' 
  AND token = 'xrJ1Fo8sso0tFGypPU57TGo+ukmvMXKDLvo/Kge07uI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}