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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6371af2905e30fa991cbf84b29947ceef0f1270d000b42011a8dde8181b29350' 
  AND token = 'iuTK+d/r1ZzJ6vLj/5HsiUESWj0Ylwedytc7D0/0pQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}