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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '307e2e8ea591b2d89166641de4f3e9ac651b10261b579b5a68248c4431e6fd0f' 
  AND token = 'w1z5ixbPEr+r/PPwsrkMnQTgqgOIAVb11vHJhQl6WnU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}