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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '748a5d758d24cfeb4952d0300440c7b445976cf9aaf28052233e4c7bfde1ce04' 
  AND token = '2RKKBDKEtQvdXFzxdE6sI6bQJkVprh2yPC3s+6SBf9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}