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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d418ed476ab6e0e2628d38f3e94296910e4fbd153f26e07d9d6c54d3e5d2472' 
  AND token = 'oJMQxLMq1w4M8ig7OY/SD3X6XpM/B2FMZwSRJ/qPMIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}