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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4654a208a6e3df4cf658a0fdb594effb10390075da5bc1020efcfddd41819d2d' 
  AND token = 'xQdw90dfewYrWaAiDazaOtw8FdHnbjz6lxK0Rwj5Dbw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}