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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43b946437bf323d74aad4605ce6523e09df5333734fa36df1e548ae500f5d67f' 
  AND token = 'GJwnHJeoN8N13F46z0uSHYq6iSlEPCduo+uUjNhN/+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}