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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7e6c3ba8cd34b07c918e865a86e4f3d30900823bef146ce767f9e0ee37b2c46' 
  AND token = '74gTS4Yw2cU07rUwZSQfrdSi6KHJmkmeHkP8aLZH6bg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}