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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4deb0ba1288a18e403ada82e7df410b501d66371d8aa683448bca043f78b7f59' 
  AND token = '339X1WCiLjy/nW1ZMpBFavHR+phrUB4bstt9XxK5EKg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}