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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06f26f6002186d8f61210b6321856cec9f793b5c103c76eb382757cba208c542' 
  AND token = '+yRczyvuVAxiMNWX0BVe8EW1ZOy0cSr+WB3bDY+/DTE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}