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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e5f737d4194d1f7b18fb48f230aa3fa8dd6eaab0a6f40da023116e16f4767a9' 
  AND token = 'iZulpGJqm31FPkZE0FAW4FWDvZ2m5HBKHBD4UYLb27s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}