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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '168501e5113ccd29a8649e33081e87b360106f1381670a775ff1ed64a97ce743' 
  AND token = 'nVCjhFRWX8h9SSE72eNon16pkKzxnmaUa0rqrUe941w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}