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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e4405bf6365ab7df52362ed5c8ad42846fb77b99ce89a9177aec692add11294' 
  AND token = 'u4XZDhltXTUKyvXK1pVJkeBsJk61ARK2sXfEt9wD/JU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}