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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2f273df97d06f7f4ba2b5b71ba07b6338f8cc7ae2876420edb5bde434c06321' 
  AND token = 'uqe/Fs7VnkStPl9Rm2w80bN2Jsp30sNmqy4S5FQvge0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}