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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26774fb9b517bd979c9aa78761cc562251cae4456795f2e2d9108ab160deaf4b' 
  AND token = 'GPWMRAODRQkT//xoxg3Xb773Ebs10uS2XAbTZ9u/gPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}