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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b46bf81b6a1eebec5a46fda423ca1bbb9fe030b6e3fbb4ea539ed72585728da7' 
  AND token = 'TydmktjYJjVNBkrt43cGubAT7JWn6UICranMm30w/F0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}