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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b159df8df943bc91cd4ad855f8a49c4fa96f23ffe082696794a43d8dea5ef8e' 
  AND token = 'r1z+rGOEahLf+ukQqPXdh4NoCt4u1iSHuugoJmsKi6w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}