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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '437f45cfc78b8ee004a869995bae7fc988a8048aa0835be888a7ebe16050e0a9' 
  AND token = '8PYJd4akoW9eb83LqrFFv+yZhhfNFLJunFC9dBUgENY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}