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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fb75d7afffb817a4f417648abac158c6218c9dc840402120d67683bab19bc2c' 
  AND token = '7a6YMFXcYphN1C05KIE+CqS5RjiByRAXTfvyNWURYPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}