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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c5753df403842cdfaabb950f0dd2bd7389dea07fbbce96a6048b72fa46997b7' 
  AND token = 'D55VFL/g62U56oVlCSU6o84wjPx2TvoC8iYtzmmtfpw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}