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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fa020b27d4e965e47b2310760041317011c3b307a2db47924c43d46d034d4bc' 
  AND token = '8SG7pREiAfpptXLJTxbndZ5MoPkYhEx1sZw5X5Gy6is=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}