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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3d425f5453a5475a67bcbc82d62cd3a60ad426cae3e861669260c9fb0cf2c1f' 
  AND token = 'Sy2sKaMXNcFY55TtDYDbi1DBUip5n49VQwbikFlMepM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}