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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e409258d2092a1e15ae727debe7c8b3572c332fa0f90782d997934ae8018f28' 
  AND token = 'm5xOVsP5C44n57zVaWvwLI8Soh3oQnDjsxwdjW6Wes4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}